A differentiation-based phylogeny of cancer subtypes.

Histopathological classification of human tumors relies in part on the degree of differentiation of the tumor sample. To date, there is no objective systematic method to categorize tumor subtypes by maturation. In this paper, we introduce a novel computational algorithm to rank tumor subtypes accord...

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Bibliographic Details
Main Authors: Markus Riester, Camille Stephan-Otto Attolini, Robert J Downey, Samuel Singer, Franziska Michor
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-05-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC2865519?pdf=render