Specialized box C/D snoRNPs act as antisense guides to target RNA base acetylation.
Box C/D snoRNAs are known to guide site-specific ribose methylation of ribosomal RNA. Here, we demonstrate a novel and unexpected role for box C/D snoRNAs in guiding 18S rRNA acetylation in yeast. Our results demonstrate, for the first time, that the acetylation of two cytosine residues in 18S rRNA...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2017-05-01
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Series: | PLoS Genetics |
Online Access: | http://europepmc.org/articles/PMC5464676?pdf=render |