A model of binding on DNA microarrays: understanding the combined effect of probe synthesis failure, cross-hybridization, DNA fragmentation and other experimental details of affymetrix arrays

<p>Abstract</p> <p>Background</p> <p>DNA microarrays are used both for research and for diagnostics. In research, Affymetrix arrays are commonly used for genome wide association studies, resequencing, and for gene expression analysis. These arrays provide large amounts...

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Bibliographic Details
Main Authors: Jakubek Yasminka A, Cutler David J
Format: Article
Language:English
Published: BMC 2012-12-01
Series:BMC Genomics
Online Access:http://www.biomedcentral.com/1471-2164/13/737