Determinants of early afterdepolarization properties in ventricular myocyte models.

Early afterdepolarizations (EADs) are spontaneous depolarizations during the repolarization phase of an action potential in cardiac myocytes. It is widely known that EADs are promoted by increasing inward currents and/or decreasing outward currents, a condition called reduced repolarization reserve....

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Bibliographic Details
Main Authors: Xiaodong Huang, Zhen Song, Zhilin Qu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-11-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1006382