Acute and Long-Term Toxicity of Mango Leaves Extract in Mice and Rats

The acute toxicity of mango leaves extract (MLE) at the maximal dose (18.4 g/kg) was studied in ICR mice and no abnormalities were detected during the experiment. The long-term studies at various doses of MLE (100 mg/kg, 300 mg/kg, and 900 mg/kg) in SD rats for 3 consecutive months revealed that, co...

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Bibliographic Details
Main Authors: Yi Zhang, Jian Li, Zhizhen Wu, Erwei Liu, Pingping Shi, Lifeng Han, Lingling Guo, Xiumei Gao, Tao Wang
Format: Article
Language:English
Published: Hindawi Limited 2014-01-01
Series:Evidence-Based Complementary and Alternative Medicine
Online Access:http://dx.doi.org/10.1155/2014/691574