Insight Into the Interaction Between RNA Polymerase and VPg for Murine Norovirus Replication

Insight Into the Interaction Between RNA Polymerase and VPg for Murine Norovirus Replication

Norovirus (NoV) is a leading cause of epidemic acute non-bacterial gastroenteritis, and replicates through virion protein genome-linked (VPg)-primed or de novo RNA synthesis by RNA-dependent RNA polymerase (RdRp). VPg is a multifunctional protein that plays crucial roles in viral protein translation...

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Bibliographic Details
Main Authors: Ji-Hye Lee, Beom Seok Park, Intekhab Alam, Kang R. Han, Scott B. Biering, Soo J. Kim, Jayoung Choi, Jong H. Seok, Mi S. Chung, Ho M. Kim, Seungmin Hwang, Kyung H. Kim
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-07-01
Series:Frontiers in Microbiology
Subjects:
norovirus
RNA-dependent RNA polymerase
VPg
interaction
viral replication
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2018.01466/full

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https://www.frontiersin.org/article/10.3389/fmicb.2018.01466/full

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