SPARK-X: non-parametric modeling enables scalable and robust detection of spatial expression patterns for large spatial transcriptomic studies

Abstract Spatial transcriptomic studies are becoming increasingly common and large, posing important statistical and computational challenges for many analytic tasks. Here, we present SPARK-X, a non-parametric method for rapid and effective detection of spatially expressed genes in large spatial tra...

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Bibliographic Details
Main Authors: Jiaqiang Zhu, Shiquan Sun, Xiang Zhou
Format: Article
Language:English
Published: BMC 2021-06-01
Series:Genome Biology
Subjects:
Online Access:https://doi.org/10.1186/s13059-021-02404-0