Improved Gene Transfer with Functionalized Hollow Mesoporous Silica Nanoparticles of Reduced Cytotoxicity

Improved Gene Transfer with Functionalized Hollow Mesoporous Silica Nanoparticles of Reduced Cytotoxicity

Gene therapy is a promising strategy for treatment of genetically caused diseases. Successful gene delivery requires an efficient carrier to transfer the desired gene into host cells. Recently, mesoporous silica nanoparticles (MSNs) functionalized with 25 kD polyethyleneimine (PEI) were extensively...

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Bibliographic Details
Main Authors: Zhengwen Zhan, Xiaoxu Zhang, Jiayuan Huang, Ying Huang, Zhengwei Huang, Xin Pan, Guilan Quan, Hu Liu, Lili Wang, and Chuanbin Wu
Format: Article
Language:English
Published: MDPI AG 2017-06-01
Series:Materials
Subjects:
hollow mesoporous silica nanoparticles
PEI
gene transfer
cytotoxicity
Online Access:http://www.mdpi.com/1996-1944/10/7/731

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http://www.mdpi.com/1996-1944/10/7/731

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