Differential astroglial responses in the spinal cord of rats submitted to a sciatic nerve double crush treated with local injection of cultured Schwann cell suspension or lesioned spinal cord extract: implications on cell therapy for nerve repair Respostas astrocitárias na medula espinal do rato submetido ao esmagamento duplo do nervo ciático e tratado com injeção local de suspensão de células de Schwann cultivadas ou de extrato de medula espinal lesada: implicações na terapia celular para o reparo do nervo

PURPOSE: Reactive astrocytes are implicated in several mechanisms after central or peripheral nervous system lesion, including neuroprotection, neuronal sprouting, neurotransmission and neuropathic pain. Schwann cells (SC), a peripheral glia, also react after nerve lesion favoring wound/repair, fibe...

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Bibliographic Details

Main Authors:	João Gabriel Martins Dallo, Bernardo Vergara Reichert, José Benedito Ramos Valladão Júnior, Camila Silva, Bianca Aparecida de Luca, Beatriz de Freitas Azevedo Levy, Gerson Chadi
Format:	Article
Language:	English
Published:	Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia 2007-12-01
Series:	Acta Cirurgica Brasileira
Subjects:	Lesão do nervo ciático Astrócito Proteção neuronal Neuroplasticidade Neurorregeneração Dor Revisão Sciatic nerve lesion Astrocyte Neuronal protection Neuroplasticity Neuroregeneration Pain Review
Online Access:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502007000600013