Duloxetine by Modulating the Akt/GSK3 Signaling Pathways Has Neuroprotective Effects against Methamphetamine-Induced Neurodegeneration and Cognition Impairment in Rats

Background: The neuroprotective effects of duloxetine, as an antidepressant agent, and the neurodegenerative effects of methamphetamine have been shown in previous studies. Nonetheless, their exact neurochemical and behavioral effects are still unclear. In the current study, we sought to clarify the...

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Bibliographic Details
Main Authors: Mehrasa Rahimi Borumand, Majid Motaghinejad, Manijeh Motevalian, Mina Gholami
Format: Article
Language:English
Published: Shiraz University of Medical Sciences 2019-03-01
Series:Iranian Journal of Medical Sciences
Subjects:
Online Access:http://ijms.sums.ac.ir/article_44515_23485ac03dababd2a542556d3c98ce0a.pdf