The RBP-Jκ binding sites within the RTA promoter regulate KSHV latent infection and cell proliferation.

Kaposi's sarcoma-associated herpesvirus (KSHV) is tightly linked to at least two lymphoproliferative disorders, primary effusion lymphoma (PEL) and multicentric Castleman's disease (MCD). However, the development of KSHV-mediated lymphoproliferative disease is not fully understood. Here, w...

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Bibliographic Details
Main Authors: Jie Lu, Subhash C Verma, Qiliang Cai, Abhik Saha, Richard Kuo Dzeng, Erle S Robertson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Pathogens
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22253595/?tool=EBI