miR-122 Exerts Inhibitory Effects on Osteoblast Proliferation/Differentiation in Osteoporosis by Activating the PCP4-Mediated JNK Pathway

miR-122 Exerts Inhibitory Effects on Osteoblast Proliferation/Differentiation in Osteoporosis by Activating the PCP4-Mediated JNK Pathway

Osteoporosis is characterized by the reduction of bone mineral density and deterioration of bone quality which leads to high risk of fractures. Some microRNAs (miRNAs) have been confirmed as potential modulators of osteoblast differentiation to maintain bone mass maintenance. We aimed to clarify whe...

Full description

Bibliographic Details
Main Authors: Yi-Chen Meng, Tao Lin, Heng Jiang, Zheng Zhang, Lun Shu, Jia Yin, Xiao Ma, Ce Wang, Rui Gao, Xu-Hui Zhou
Format: Article
Language:English
Published: Elsevier 2020-06-01
Series:Molecular Therapy: Nucleic Acids
Subjects:
osteoporosis
microRNA-122
PCP4
JNK signaling pathway
osteoblasts
proliferation
Online Access:http://www.sciencedirect.com/science/article/pii/S2162253120300159

Internet

http://www.sciencedirect.com/science/article/pii/S2162253120300159

Similar Items