Cell-permeable transgelin-2 as a potent therapeutic for dendritic cell-based cancer immunotherapy

Cell-permeable transgelin-2 as a potent therapeutic for dendritic cell-based cancer immunotherapy

Abstract Background Transgelin-2 is a 22 kDa actin-binding protein that has been proposed to act as an oncogenic factor, capable of contributing to tumorigenesis in a wide range of human malignancies. However, little is known whether this tiny protein also plays an important role in immunity, thereb...

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Bibliographic Details
Main Authors: Hye-Ran Kim, Jeong-Su Park, Jin-Hwa Park, Fatima Yasmin, Chang-Hyun Kim, Se Kyu Oh, Ik-Joo Chung, Chang-Duk Jun
Format: Article
Language:English
Published: BMC 2021-03-01
Series:Journal of Hematology & Oncology
Subjects:
Transgelin-2
T-cell priming
Migration
Immunological synapse
Cell-permeable recombinant protein
Dendritic cell-based cancer therapy
Online Access:https://doi.org/10.1186/s13045-021-01058-6

Internet

https://doi.org/10.1186/s13045-021-01058-6

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