Compensation for chronic oxidative stress in ALADIN null mice

Compensation for chronic oxidative stress in ALADIN null mice

Mutations in the AAAS gene coding for the nuclear pore complex protein ALADIN lead to the autosomal recessive disorder triple A syndrome. Triple A patients present with a characteristic phenotype including alacrima, achalasia and adrenal insufficiency. Patient fibroblasts show increased levels of ox...

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Bibliographic Details
Main Authors: Ramona Jühlen, Mirko Peitzsch, Sebastian Gärtner, Dana Landgraf, Graeme Eisenhofer, Angela Huebner, Katrin Koehler
Format: Article
Language:English
Published: The Company of Biologists 2018-01-01
Series:Biology Open
Subjects:
ALADIN
Oxidative stress
Paraquat
Redox homeostasis
Triple A syndrome
Online Access:http://bio.biologists.org/content/7/1/bio030742

Internet

http://bio.biologists.org/content/7/1/bio030742

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