Resilience, plasticity and robustness in gene expression during aging in the brain of outbred deer mice

Abstract Background Genes that belong to the same network are frequently co-expressed, but collectively, how the coordination of the whole transcriptome is perturbed during aging remains unclear. To explore this, we calculated the correlation of each gene in the transcriptome with every other, in th...

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Bibliographic Details
Main Authors: E Soltanmohammadi, Y Zhang, I Chatzistamou, H. Kiaris
Format: Article
Language:English
Published: BMC 2021-04-01
Series:BMC Genomics
Subjects:
Online Access:https://doi.org/10.1186/s12864-021-07613-2