The effect of heparan sulfate application on bone formation during distraction osteogenesis.

Bone morphogenetic proteins (BMPs) are recognized for their ability to induce bone formation in vivo and in vitro. Their osteogenic and osteoinductive properties are tightly regulated by the secretion of specific BMP antagonists, which have been shown to physically bind and sometimes be blocked by t...

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Bibliographic Details
Main Authors: Marie Gdalevitch, Bahar Kasaai, Norine Alam, Bruno Dohin, Dominique Lauzier, Reggie C Hamdy
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3574072?pdf=render