Effect of GSDMD-mediated pyroptosis on muscle atrophy of skeletal muscle in mice and its potential mechanism

Effect of GSDMD-mediated pyroptosis on muscle atrophy of skeletal muscle in mice and its potential mechanism

Objective To investigate the occurrence of gasdermin D protein (GSDMD)-mediated pyroptosis and muscle atrophy in mice under lipopolysaccharide (LPS) stimulation in order to elucidate the possible pathogenetic mechanisms of intensive care unit-acquired weakness (ICU-AW). Methods The mouse skeletal mu...

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Bibliographic Details
Main Authors: LI Mei, LI Shuang, HU Jian, LIN Zhengxiao, ZHANG Guirong, LIU Sha, LI Fuxiang
Format: Article
Language:zho
Published: Editorial Office of Journal of Third Military Medical University 2021-08-01
Series:Di-san junyi daxue xuebao
Subjects:
icu-acquired weakness
critical illness myopathy
muscular atrophy
myotubes
lipopolysaccharide
pyroptosis
Online Access:http://aammt.tmmu.edu.cn/Upload/rhtml/202101229.htm

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http://aammt.tmmu.edu.cn/Upload/rhtml/202101229.htm

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