The 5-HTTLPR-rs25531 S-A-S-A Haplotype and Chronic Stress Moderate the Association Between Acute Stress and Internalizing Mental Disorders Among HIV+ Children and Adolescents in Uganda

The 5-HTTLPR-rs25531 S-A-S-A Haplotype and Chronic Stress Moderate the Association Between Acute Stress and Internalizing Mental Disorders Among HIV+ Children and Adolescents in Uganda

Background: Internalizing mental disorders (IMDs) among HIV-positive (HIV+) children and adolescents are associated with poor disease outcomes, such as faster HIV disease progression. Although it has been suggested that the development of IMDs is moderated by interaction of stressful life events and...

Full description

Bibliographic Details
Main Authors: Allan Kalungi, Jacqueline S. Womersley, Eugene Kinyanda, Moses L. Joloba, Wilber Ssembajjwe, Rebecca N. Nsubuga, Soraya Seedat, Sian M. J. Hemmings
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Genetics
Subjects:
internalizing mental disorders
acute stress
serotonin transporter gene
5-HTTLPR-rs25531
chronic stress
HIV+ children and adolescents
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2021.649055/full

Internet

https://www.frontiersin.org/articles/10.3389/fgene.2021.649055/full

Similar Items