Cytostasis and morphological changes induced by mifepristone in human metastatic cancer cells involve cytoskeletal filamentous actin reorganization and impairment of cell adhesion dynamics

<p>Abstract</p> <p>Background</p> <p>Changes in cell shape and plasticity in cytoskeletal dynamics are critically involved in cell adhesion, migration, invasion and the overall process of metastasis. Previous work in our laboratory demonstrated that the synthetic steroi...

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Bibliographic Details
Main Authors: Brandhagen BreeAnn N, Tieszen Chelsea R, Ulmer Tara M, Tracy Maria S, Goyeneche Alicia A, Telleria Carlos M
Format: Article
Language:English
Published: BMC 2013-01-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/13/35