Diet1, bile acid diarrhea, and FGF15/19: mouse model and human genetic variants[S]

Diet1, bile acid diarrhea, and FGF15/19: mouse model and human genetic variants[S]

Diet1 modulates intestinal production of the hormone, fibroblast growth factor (FGF)15, which signals in liver to regulate bile acid synthesis. C57BL/6ByJ mice with a spontaneous Diet1-null mutation are resistant to hypercholesterolemia compared with wild-type C57BL/6J mice through enhanced choleste...

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Bibliographic Details
Main Authors: Jessica M. Lee, Jessica R. Ong, Laurent Vergnes, Thomas Q. de Aguiar Vallim, Jonathan Nolan, Rita M. Cantor, JulianR.F. Walters, Karen Reue
Format: Article
Language:English
Published: Elsevier 2018-03-01
Series:Journal of Lipid Research
Subjects:
intestine
fibroblast growth factor 15/19
Hybrid Mouse Diversity Panel
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520331321

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http://www.sciencedirect.com/science/article/pii/S0022227520331321

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