Evidence for the Existence of Triple-Negative Variants in the MCF-7 Breast Cancer Cell Population

The MCF-7 line, derived in 1973 from a malignant pleural effusion, is one of the most commonly used culture models for human breast cancer. Despite its long history, MCF-7 is a surprisingly heterogeneous line. We previously showed that if MCF-7 cells were cultured for a prolonged period either in th...

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Bibliographic Details
Main Authors: Euphemia Leung, Ji Eun Kim, Marjan Askarian-Amiri, Graeme J. Finlay, Bruce C. Baguley
Format: Article
Language:English
Published: Hindawi Limited 2014-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2014/836769