Salmonella-induced mucosal lectin RegIIIβ kills competing gut microbiota.

Intestinal inflammation induces alterations of the gut microbiota and promotes overgrowth of the enteric pathogen Salmonella enterica by largely unknown mechanisms. Here, we identified a host factor involved in this process. Specifically, the C-type lectin RegIIIβ is strongly upregulated during muco...

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Bibliographic Details
Main Authors: Christian Stelter, Rina Käppeli, Claudia König, Alexander Krah, Wolf-Dietrich Hardt, Bärbel Stecher, Dirk Bumann
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3111430?pdf=render