Reprogramming of Yersinia from virulent to persistent mode revealed by complex in vivo RNA-seq analysis.

We recently found that Yersinia pseudotuberculosis can be used as a model of persistent bacterial infections. We performed in vivo RNA-seq of bacteria in small cecal tissue biopsies at early and persistent stages of infection to determine strategies associated with persistence. Comprehensive analysi...

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Bibliographic Details
Main Authors: Kemal Avican, Anna Fahlgren, Mikael Huss, Ann Kathrin Heroven, Michael Beckstette, Petra Dersch, Maria Fällman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC4295882?pdf=render