Dynamic regulation of chromatin accessibility by pluripotency transcription factors across the cell cycle
The pioneer activity of transcription factors allows for opening of inaccessible regulatory elements and has been extensively studied in the context of cellular differentiation and reprogramming. In contrast, the function of pioneer activity in self-renewing cell divisions and across the cell cycle...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2019-12-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/50087 |