Dynamic regulation of chromatin accessibility by pluripotency transcription factors across the cell cycle

The pioneer activity of transcription factors allows for opening of inaccessible regulatory elements and has been extensively studied in the context of cellular differentiation and reprogramming. In contrast, the function of pioneer activity in self-renewing cell divisions and across the cell cycle...

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Bibliographic Details
Main Authors: Elias T Friman, Cédric Deluz, Antonio CA Meireles-Filho, Subashika Govindan, Vincent Gardeux, Bart Deplancke, David M Suter
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2019-12-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/50087