A piggyBac-based TANGO GFP assay for high throughput screening of GPCR ligands in live cells

Abstract Background GPCRs are considered essential for various physiological processes and have been the most productive drug targets. Therefore, development of the methods of GPCR ligands screening is a high priority for pharmaceutical industries and research institutions. Methods We developed a po...

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Bibliographic Details
Main Authors: Fei Li, Xi Jiang, Ling-Ling Luo, Yue-Ming Xu, Xing-Xu Huang, Cheng Huang, Yu Zhang
Format: Article
Language:English
Published: BMC 2019-05-01
Series:Cell Communication and Signaling
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12964-019-0359-x