ALDH activity selectively defines an enhanced tumor-initiating cell population relative to CD133 expression in human pancreatic adenocarcinoma.

ALDH activity selectively defines an enhanced tumor-initiating cell population relative to CD133 expression in human pancreatic adenocarcinoma.

Multiple studies in recent years have identified highly tumorigenic populations of cells that drive tumor formation. These cancer stem cells (CSCs), or tumor-initiating cells (TICs), exhibit properties of normal stem cells and are associated with resistance to current therapies. As pancreatic adenoc...

Full description

Bibliographic Details
Main Authors: Michael P Kim, Jason B Fleming, Huamin Wang, James L Abbruzzese, Woonyoung Choi, Scott Kopetz, David J McConkey, Douglas B Evans, Gary E Gallick
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3113804?pdf=render

Internet

http://europepmc.org/articles/PMC3113804?pdf=render

Similar Items