Erythrocyte P2X1 receptor expression is correlated with change in haematocrit in patients admitted to the ICU with blood pathogen-positive sepsis

Erythrocyte P2X1 receptor expression is correlated with change in haematocrit in patients admitted to the ICU with blood pathogen-positive sepsis

Abstract Background Pore-forming proteins released from bacteria or formed as result of complement activation are known to produce severe cell damage. Inhibition of purinergic P2X receptors markedly reduces damage inflicted by cytolytic bacterial toxin and after complement activation in both erythro...

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Bibliographic Details
Main Authors: Steen K. Fagerberg, Parth Patel, Lars W. Andersen, Xiaowen Lui, Michael W. Donnino, Helle A. Praetorius
Format: Article
Language:English
Published: BMC 2018-08-01
Series:Critical Care
Subjects:
Sepsis
P2X
Toxins
Haemolysis
Anaemia
Exotoxemia/endotoxemia
Online Access:http://link.springer.com/article/10.1186/s13054-018-2100-3

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http://link.springer.com/article/10.1186/s13054-018-2100-3

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