Pituitary Adenylate Cyclase-Activating Peptide (PACAP)-Glutamate Co-transmission Drives Circadian Phase-Advancing Responses to Intrinsically Photosensitive Retinal Ganglion Cell Projections by Suprachiasmatic Nucleus

Pituitary Adenylate Cyclase-Activating Peptide (PACAP)-Glutamate Co-transmission Drives Circadian Phase-Advancing Responses to Intrinsically Photosensitive Retinal Ganglion Cell Projections by Suprachiasmatic Nucleus

Results from a variety of sources indicate a role for pituitary adenylate cyclase-activating polypeptide (PACAP) in light/glutamate-induced phase resetting of the circadian clock mediated by the retinohypothalamic tract (RHT). Attempts to block or remove PACAP’s contribution to clock-resetting have...

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Bibliographic Details
Main Authors: Peder T. Lindberg, Jennifer W. Mitchell, Penny W. Burgoon, Christian Beaulé, Eberhard Weihe, Martin K.-H. Schäfer, Lee E. Eiden, Sunny Z. Jiang, Martha U. Gillette
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-12-01
Series:Frontiers in Neuroscience
Subjects:
PACAP
glutamate
suprachiasmatic nucleus
circadian rhythm
phase advance
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2019.01281/full

Internet

https://www.frontiersin.org/article/10.3389/fnins.2019.01281/full

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