Peroxisome proliferator-activated receptors γ/mitochondrial uncoupling protein 2 signaling protects against seizure-induced neuronal cell death in the hippocampus following experimental status epilepticus

Peroxisome proliferator-activated receptors γ/mitochondrial uncoupling protein 2 signaling protects against seizure-induced neuronal cell death in the hippocampus following experimental status epilepticus

<p>Abstract</p> <p>Background</p> <p>Status epilepticus induces subcellular changes that may lead to neuronal cell death in the hippocampus. However, the mechanism of seizure-induced neuronal cell death remains unclear. The mitochondrial uncoupling protein 2 (UCP2) is e...

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Bibliographic Details
Main Authors: Chuang Yao-Chung, Lin Tsu-Kung, Huang Hsuan-Ying, Chang Wen-Neng, Liou Chia-Wei, Chen Shang-Der, Chang Alice YW, Chan Samuel HH
Format: Article
Language:English
Published: BMC 2012-07-01
Series:Journal of Neuroinflammation
Subjects:
Status epilepticus
Mitochondrial uncoupling protein 2
Peroxisome proliferator-activated receptors γ
Hippocampal neuronal cell death
Oxidative stress
Online Access:http://www.jneuroinflammation.com/content/9/1/184

Internet

http://www.jneuroinflammation.com/content/9/1/184

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