Role of Inflammatory Factors during Disease Pathogenesis and Stem Cell Transplantation in Myeloproliferative Neoplasms

Role of Inflammatory Factors during Disease Pathogenesis and Stem Cell Transplantation in Myeloproliferative Neoplasms

Hematopoiesis is a highly regulated and complex process involving hematopoietic stem cells (HSCs), cell surface adhesion molecules, and cytokines as well as cells of the hematopoietic niche in the bone marrow (BM). Myeloproliferative neoplasms (MPNs) are characterized by clonal expansion of HSCs inv...

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Bibliographic Details
Main Authors: Nicolas Chatain, Steffen Koschmieder, Edgar Jost
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Cancers
Subjects:
myeloproliferative neoplasm
inflammation
cytokines
allogeneic hematopoietic stem cell transplantation
JAK inhibitors
Online Access:https://www.mdpi.com/2072-6694/12/8/2250

Internet

https://www.mdpi.com/2072-6694/12/8/2250

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