RIG-I is responsible for activation of type I interferon pathway in Seneca Valley virus-infected porcine cells to suppress viral replication

RIG-I is responsible for activation of type I interferon pathway in Seneca Valley virus-infected porcine cells to suppress viral replication

Abstract Background Retinoic acid-inducible gene I (RIG-I) is a key cytosolic receptor of the innate immune system. Seneca valley virus (SVV) is a newly emerging RNA virus that infects pigs causing significant economic losses in pig industry. RIG-I plays different roles during different viruses infe...

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Bibliographic Details
Main Authors: Pengfei Li, Xiangle Zhang, Weijun Cao, Fan Yang, Xiaoli Du, Zhengwang Shi, Miaotao Zhang, Xiangtao Liu, Zixiang Zhu, Haixue Zheng
Format: Article
Language:English
Published: BMC 2018-10-01
Series:Virology Journal
Subjects:
RIG-I
SVV
Interferon
Immune response
Viral replication
Online Access:http://link.springer.com/article/10.1186/s12985-018-1080-x

Internet

http://link.springer.com/article/10.1186/s12985-018-1080-x

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