Optimization of the Preparation Conditions of Borneol-Modified Ginkgolide Liposomes by Response Surface Methodology and Study of Their Blood Brain Barrier Permeability

Optimization of the Preparation Conditions of Borneol-Modified Ginkgolide Liposomes by Response Surface Methodology and Study of Their Blood Brain Barrier Permeability

Ginkgolides (GG), containing ginkgolide A (GA), ginkgolide B (GB) and ginkgolide C (GC), are mainly prescribed for ischemic stroke and cerebral infarction. However, the ginkgolides can hardly pass the blood-brain barrier (BBB) into the brain. The purpose of this study was to prepare borneol-modified...

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Bibliographic Details
Main Authors: Zhiyang Lv, Yuwei Yang, Jie Wang, Jing Chen, Junsong Li, Liuqing Di
Format: Article
Language:English
Published: MDPI AG 2018-01-01
Series:Molecules
Subjects:
ginkgolides
liposome
borneol
response surface methodology
blood-brain barrier permeability
Online Access:http://www.mdpi.com/1420-3049/23/2/303

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http://www.mdpi.com/1420-3049/23/2/303

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