A single chromosome strain of S. cerevisiae exhibits diminished ethanol metabolism and tolerance

Abstract Background Eukaryotic organisms, like the model yeast S. cerevisiae, have linear chromosomes that facilitate organization and protection of nuclear DNA. A recent work described a stepwise break/repair method that enabled fusion of the 16 chromosomes of S. cerevisiae into a single large chro...

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Bibliographic Details
Main Authors: Tyler W. Doughty, Rosemary Yu, Lucy Fang-I Chao, Zhongjun Qin, Verena Siewers, Jens Nielsen
Format: Article
Language:English
Published: BMC 2021-09-01
Series:BMC Genomics
Online Access:https://doi.org/10.1186/s12864-021-07947-x