S100B is required for maintaining an intermediate state with double-positive Sca-1+ progenitor and vascular smooth muscle cells during neointimal formation

S100B is required for maintaining an intermediate state with double-positive Sca-1+ progenitor and vascular smooth muscle cells during neointimal formation

Abstract Introduction Accumulation of vascular smooth muscle cells (VSMCs) within the neointimal region is a hallmark of atherosclerosis and vessel injury. Evidence has shown that Sca-1-positive (Sca-1+) progenitor cells residing in the vascular adventitia play a crucial role in VSMC assemblages and...

Full description

Bibliographic Details
Main Authors: Yan Wu, Xin Liu, Ling-Yun Guo, Lei Zhang, Fei Zheng, Shan Li, Xing-Yuan Li, Ye Yuan, Yu Liu, Yu-wen Yan, Shi-You Chen, Jia-Ning Wang, Jin-xuan Zhang, Jun-Ming Tang
Format: Article
Language:English
Published: BMC 2019-09-01
Series:Stem Cell Research & Therapy
Subjects:
S100B
Sca-1
Intermediate state
Neointima
SDF-1α
NF-κB
Online Access:http://link.springer.com/article/10.1186/s13287-019-1400-0

Internet

http://link.springer.com/article/10.1186/s13287-019-1400-0

Similar Items