Chemical Synthesis and Functional Analysis of VarvA Cyclotide

Chemical Synthesis and Functional Analysis of VarvA Cyclotide

Cyclotides are circular peptides found in various plant families. A cyclized backbone, together with multiple disulfide bonds, confers the peptides’ exceptional stability against protease digestion and thermal denaturation. In addition, the features of these antimicrobial molecules make th...

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Bibliographic Details
Main Authors: Claudio A. Álvarez, Paula A. Santana, Omar Luna, Constanza Cárdenas, Fernando Albericio, María S. Romero, Fanny Guzmán
Format: Article
Language:English
Published: MDPI AG 2018-04-01
Series:Molecules
Subjects:
cyclotide
antimicrobial activity
fish pathogens
membrane damage
Online Access:http://www.mdpi.com/1420-3049/23/4/952

Internet

http://www.mdpi.com/1420-3049/23/4/952

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