Skeletal muscle healing by M1-like macrophages produced by transient expression of exogenous GM-CSF

Skeletal muscle healing by M1-like macrophages produced by transient expression of exogenous GM-CSF

Abstract Background After traumatic skeletal muscle injury, muscle healing is often incomplete and produces extensive fibrosis. The sequence of M1 and M2 macrophage accumulation and the duration of each subtype in the injured area may help to direct the relative extent of fibrogenesis and myogenesis...

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Bibliographic Details
Main Authors: Leonardo Martins, Camila Congentino Gallo, Tâmisa Seeko Bandeira Honda, Patrícia Terra Alves, Roberta Sessa Stilhano, Daniela Santoro Rosa, Timothy Jon Koh, Sang Won Han
Format: Article
Language:English
Published: BMC 2020-11-01
Series:Stem Cell Research & Therapy
Subjects:
Fibrosis
Skeletal muscle
Injury
Myogenesis
GM-CSF
Macrophage
Online Access:http://link.springer.com/article/10.1186/s13287-020-01992-1

Internet

http://link.springer.com/article/10.1186/s13287-020-01992-1

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