Relatively low level of antigen-specific monocytes detected in blood from untreated tuberculosis patients using CD4+ T-cell receptor tetramers.

Relatively low level of antigen-specific monocytes detected in blood from untreated tuberculosis patients using CD4+ T-cell receptor tetramers.

The in vivo kinetics of antigen-presenting cells (APCs) in patients with advanced and convalescent tuberculosis (TB) is not well characterized. In order to target Mycobacterium tuberculosis (MTB) peptides- and HLA-DR-holding monocytes and macrophages, 2 MTB peptide-specific CD4(+) T-cell receptor (T...

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Bibliographic Details
Main Authors: Yuhong Huang, Yan Huang, Yimin Fang, Juan Wang, Yan Li, Nan Wang, Jianbo Zhang, Ming Gao, Lirong Huang, Fangfang Yang, Cong Wang, Shuxian Lin, Yanan Yao, Liangliang Ren, Yi Chen, Xuanjing Du, Dan Xie, Rongshun Wu, Kouxing Zhang, Lifang Jiang, Xinbing Yu, Xiaomin Lai
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3510242?pdf=render

Internet

http://europepmc.org/articles/PMC3510242?pdf=render

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