HIV-1 Latency: An Update of Molecular Mechanisms and Therapeutic Strategies
The major obstacle towards HIV-1 eradication is the life-long persistence of the virus in reservoirs of latently infected cells. In these cells the proviral DNA is integrated in the host’s genome but it does not actively replicate, becoming invisible to the host immune system and unaffected by exist...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2014-04-01
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Series: | Viruses |
Subjects: | |
Online Access: | http://www.mdpi.com/1999-4915/6/4/1715 |