HIV-1 Latency: An Update of Molecular Mechanisms and Therapeutic Strategies

The major obstacle towards HIV-1 eradication is the life-long persistence of the virus in reservoirs of latently infected cells. In these cells the proviral DNA is integrated in the host’s genome but it does not actively replicate, becoming invisible to the host immune system and unaffected by exist...

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Bibliographic Details
Main Authors: Angela Battistini, Marco Sgarbanti
Format: Article
Language:English
Published: MDPI AG 2014-04-01
Series:Viruses
Subjects:
HIV
Online Access:http://www.mdpi.com/1999-4915/6/4/1715