Increase in Red Blood Cell-Nitric Oxide Synthase Dependent Nitric Oxide Production during Red Blood Cell Aging in Health and Disease: A Study on Age Dependent Changes of Rheologic and Enzymatic Properties in Red Blood Cells.

<h4>Aim</h4>To investigate RBC-NOS dependent NO signaling during in vivo RBC aging in health and disease.<h4>Method</h4>RBC from fifteen healthy volunteers (HC) and four patients with type 2 diabetes mellitus (DM) were separated in seven subpopulations by Percoll density grad...

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Bibliographic Details
Main Authors: Daniel Alexander Bizjak, Christian Brinkmann, Wilhelm Bloch, Marijke Grau
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0125206