Cardiomyocyte Contractility and Autophagy in a Premature Senescence Model of Cardiac Aging

Globally, cardiovascular diseases are the leading cause of death in the aging population. While the clinical pathology of the aging heart is thoroughly characterized, underlying molecular mechanisms are still insufficiently clarified. The aim of the present study was to establish an in vitro model s...

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Bibliographic Details
Main Authors: Steffen Häseli, Stefanie Deubel, Tobias Jung, Tilman Grune, Christiane Ott
Format: Article
Language:English
Published: Hindawi Limited 2020-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.1155/2020/8141307