Co-Delivery of Gemcitabine and Paclitaxel in cRGD-Modified Long Circulating Nanoparticles with Asymmetric Lipid Layers for Breast Cancer Treatment

Co-Delivery of Gemcitabine and Paclitaxel in cRGD-Modified Long Circulating Nanoparticles with Asymmetric Lipid Layers for Breast Cancer Treatment

Combination chemotherapy is a common clinical practice in cancer treatment. Here, cyclic RGD (arginylglycylaspartic acid) peptide was introduced to the surface of lipid/calcium/phosphate (LCP) asymmetric lipid layer nanoparticles for the co-delivery of paclitaxel (PTX) and gemcitabine monophosphate...

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Bibliographic Details
Main Authors: Jing Zhang, Peng Zhang, Qian Zou, Xiang Li, Jianjiang Fu, Ying Luo, Xinli Liang, Yi Jin
Format: Article
Language:English
Published: MDPI AG 2018-11-01
Series:Molecules
Subjects:
paclitaxel
gemcitabine monophosphate
cyclic RGD
pharmacokinetics
antitumor efficacy
Online Access:https://www.mdpi.com/1420-3049/23/11/2906

Internet

https://www.mdpi.com/1420-3049/23/11/2906

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