Endothelin-1 contributes to the development of virus-induced demyelinating disease

Abstract Background Experimental autoimmune encephalitis (EAE) and virally induced demyelinating disease are two major experimental model systems used to study human multiple sclerosis. Although endothelin-1 level elevation was previously observed in the CNS of mice with EAE and viral demyelinating...

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Bibliographic Details
Main Authors: Young-Hee Jin, Bongsu Kang, Hyun S. Kang, Chang-Sung Koh, Byung S. Kim
Format: Article
Language:English
Published: BMC 2020-10-01
Series:Journal of Neuroinflammation
Subjects:
CNS
EAE
Online Access:http://link.springer.com/article/10.1186/s12974-020-01986-z