Microglial activation mediates chronic mild stress-induced depressive- and anxiety-like behavior in adult rats

Microglial activation mediates chronic mild stress-induced depressive- and anxiety-like behavior in adult rats

Abstract Background Depression is a heterogeneous disorder, with the exact neuronal mechanisms causing the disease yet to be discovered. Recent work suggests it is accompanied by neuro-inflammation, characterized, in particular, by microglial activation. However, microglial activation and its involv...

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Bibliographic Details
Main Authors: Ya-Lin Wang, Qiu-Qin Han, Wen-Qing Gong, Dong-Hui Pan, Li-Zheng Wang, Wei Hu, Min Yang, Bing Li, Jin Yu, Qiong Liu
Format: Article
Language:English
Published: BMC 2018-01-01
Series:Journal of Neuroinflammation
Subjects:
Depression
Microglia
Inflammation
NLRP3 inflammasome
Minocycline
Online Access:http://link.springer.com/article/10.1186/s12974-018-1054-3

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http://link.springer.com/article/10.1186/s12974-018-1054-3

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