Identifying the active components of Baihe–Zhimu decoction that ameliorate depressive disease by an effective integrated strategy: a systemic pharmacokinetics study combined with classical depression model tests

Identifying the active components of Baihe–Zhimu decoction that ameliorate depressive disease by an effective integrated strategy: a systemic pharmacokinetics study combined with classical depression model tests

Abstract Background Modern pharmacological studies have demonstrated that Baihe–Zhimu decoction (BZD) has antidepressant effects. However, the complex composition and lack of clear evaluation standards for BZD make it less likely to be understood and accepted than evidence-based active natural compo...

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Bibliographic Details
Main Authors: Ming Zhong, Xiaoting Tian, Shuoji Chen, Mingcang Chen, Ziqiong Guo, Minna Zhang, Gongpu Zheng, Zhixiong Li, Zhangpeng Shi, Guanghui Wang, Honggang Gao, Fang Liu, Chenggang Huang
Format: Article
Language:English
Published: BMC 2019-09-01
Series:Chinese Medicine
Subjects:
Baihe–Zhimu decoction
Antidepressant
Timosaponin BII
Timosaponin BIII
Drug discovery
Online Access:http://link.springer.com/article/10.1186/s13020-019-0254-9

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http://link.springer.com/article/10.1186/s13020-019-0254-9

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