Single bout short duration fluid shear stress induces osteogenic differentiation of MC3T3-E1 cells via integrin β1 and BMP2 signaling cross-talk.

Single bout short duration fluid shear stress induces osteogenic differentiation of MC3T3-E1 cells via integrin β1 and BMP2 signaling cross-talk.

Fluid shear stress plays an important role in bone osteogenic differentiation. It is traditionally believed that pulsed and continuous stress load is more favorable for fracture recovery and bone homeostasis. However, according to our clinical practice, we notice that one single stress load is also...

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Bibliographic Details
Main Authors: Zhihui Mai, Zhuli Peng, Sihan Wu, Jinglan Zhang, Lin Chen, Huangyou Liang, Ding Bai, Guangmei Yan, Hong Ai
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3623893?pdf=render

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http://europepmc.org/articles/PMC3623893?pdf=render

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