β-Carotene conversion to vitamin A delays atherosclerosis progression by decreasing hepatic lipid secretion in mice

β-Carotene conversion to vitamin A delays atherosclerosis progression by decreasing hepatic lipid secretion in mice

Atherosclerosis is characterized by the pathological accumulation of cholesterol-laden macrophages in the arterial wall. Atherosclerosis is also the main underlying cause of CVDs, and its development is largely driven by elevated plasma cholesterol. Strong epidemiological data find an inverse associ...

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Bibliographic Details
Main Authors: Felix Zhou, Xiaoyun Wu, Ivan Pinos, Benjamin M. Abraham, Tessa J. Barrett, Johannes von Lintig, Edward A. Fisher, Jaume Amengual
Format: Article
Language:English
Published: Elsevier 2020-11-01
Series:Journal of Lipid Research
Subjects:
retinoids
retinoic acid
cholesterol
very low density lipoprotein
carotenoids
foam cells
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520437356

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http://www.sciencedirect.com/science/article/pii/S0022227520437356

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