Brusatol Enhances the Chemotherapy Efficacy of Gemcitabine in Pancreatic Cancer via the Nrf2 Signalling Pathway

Although gemcitabine is the standard chemotherapy treatment for advanced pancreatic cancer, its benefits are quite limited due to prevalent chemoresistance, and the mechanism underlying gemcitabine chemoresistance remains unclear. Currently, Nrf2 has been deemed as a significant contributor to gemci...

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Bibliographic Details
Main Authors: Yukai Xiang, Wen Ye, Chaohao Huang, Dinglai Yu, Hao Chen, Tuo Deng, Fan Zhang, Bin Lou, Jie Zhang, Keqing Shi, Bicheng Chen, Mengtao Zhou
Format: Article
Language:English
Published: Hindawi Limited 2018-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.1155/2018/2360427