Secreted Gaussia princeps luciferase as a reporter of Escherichia coli replication in a mouse tissue cage model of infection.

Secreted Gaussia princeps luciferase as a reporter of Escherichia coli replication in a mouse tissue cage model of infection.

Measurement of bacterial burden in animal infection models is a key component for both bacterial pathogenesis studies and therapeutic agent research. The traditional quantification means for in vivo bacterial burden requires frequent animal sacrifice and enumerating colony forming units (CFU) recove...

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Bibliographic Details
Main Authors: Mingyu Liu, Christina Blinn, Sarah M McLeod, John W Wiseman, Joseph V Newman, Stewart L Fisher, Grant K Walkup
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3942414?pdf=render

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http://europepmc.org/articles/PMC3942414?pdf=render

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