Model Validation and Process Design of Continuous Single Pass Tangential Flow Filtration Focusing on Continuous Bioprocessing for High Protein Concentrations

In this study, the continuous Single-Pass Tangential Flow Filtration (SPTFF) concept is adapted for high protein concentrations. The work is based on the previously validated physico-chemical model for low concentrations and high viscosities. The model contains the Stagnant Film Model for concentrat...

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Bibliographic Details
Main Authors: Maximilian Johannes Huter, Christoph Jensch, Jochen Strube
Format: Article
Language:English
Published: MDPI AG 2019-11-01
Series:Processes
Subjects:
Online Access:https://www.mdpi.com/2227-9717/7/11/781