Replicative senescence of mesenchymal stem cells: a continuous and organized process.

Replicative senescence of mesenchymal stem cells: a continuous and organized process.

Mesenchymal stem cells (MSC) comprise a promising tool for cellular therapy. These cells are usually culture expanded prior to their application. However, a precise molecular definition of MSC and the sequel of long-term in vitro culture are yet unknown. In this study, we have addressed the impact o...

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Bibliographic Details
Main Authors: Wolfgang Wagner, Patrick Horn, Mirco Castoldi, Anke Diehlmann, Simone Bork, Rainer Saffrich, Vladimir Benes, Jonathon Blake, Stefan Pfister, Volker Eckstein, Anthony D Ho
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2374903?pdf=render

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http://europepmc.org/articles/PMC2374903?pdf=render

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